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Patterson Rosa, L., Troop, T. W., Martin, K., Vierra, M., Foster, G., Lundquist, E., Brooks, S. A., & Lafayette, C. (2021). Hereditary Equine Regional Dermal Asthenia homozygote adult working horse with mild signs - A Case Report. Journal of Equine Veterinary Science, 106, 103756.
Martin, K., Brooks, S., Vierra, M., Lafayette, W. T., McClure, S., Carpenter, M., & Lafayette, C. (2020). Fragile Foal Syndrome (PLOD1 c.2032G>A) occurs across diverse horse populations. Animal Genetics, 52(1), 137–138.
Patterson Rosa, L., Whitaker, B., Allen, K., Peters, D., Buchanan, B., McClure, S., Honnas, C., Buchanan, C., Martin, K., Lundquist, E., Vierra, M., Foster, G., Brooks, S., & Lafayette, C. (2022). Genomic loci associated with performance limiting equine overriding spinous processes (kissing spines). Research in Veterinary Science, 150, 65-71.
Patterson Rosa, L., Staiger, E. A., Martin, K., Vierra, M., Foster, G., Lundquist, E., Brooks, S. A., & Lafayette, C. (2021). Stock-type equine disciplines Hunter, Reining and Roping are associated with the A allele at the DMRT3 locus for gait phenotypes in the horse. Animal Genetics, 10.1111/age.13110.
Gaspar, M. C., Campos, F. A., Staiger, E. A., Martin, K., Vierra, M., Foster, G., ... & Lafayette, C. (2021). Disciplinas esportivas em cavalos de raças de trabalho são associadas ao alelo A no locus DMRT3. Equina, 15, 4-8.
Obradovic, N. A., McFadden, A., Martin, K., Vierra, M., McLoone, K., Martin, E., ... & Lafayette, C. (2025). Three Novel KIT Polymorphisms Found in Horses with White Coat Color Phenotypes. Animals, 15(7), 915.
McFadden, A., Vierra, M., Martin, K., Brooks, S. A., Everts, R. E., & Lafayette, C. (2024). Spotting the Pattern: A Review on White Coat Color in the Domestic Horse. Animals , 14(3), 451.
McFadden, A., Martin, K., Vierra, M., Robilliard, H., Lundquist, E. W., Everts, R. E., Brooks, S. A., & Lafayette, C. (2024). Three HPS5 mutations associated with depigmentation in diverse horse breeds. Livestock Science, 282, 105454.
McFadden, A., Vierra, M., Robilliard, H., Martin, K., Brooks, S. A., Everts, R. E., & Lafayette, C. (2024). Population Analysis Identifies 15 Multi-Variant Dominant White Haplotypes in Horses. Animals, 14(3), 517.
McFadden, A., Martin, K., Foster, G., Vierra, M., Lundquist, E. W., Everts, R. E., Martin, E., Volz, E., McLoone, K., Brooks, S. A., & Lafayette, C. (2023). Two Novel Variants in MITF and PAX3 Associated With Splashed White Phenotypes in Horses. [_Journal of Equine Veterinary Science-}(https://doi.org/10.1016/j.jevs.2023.104875), 128, 104875.
McFadden, A., Martin, K., Foster, G., Vierra, M., Lundquist, E. W., Everts, R. E., Martin, E., Volz, E., McLoone, K., Brooks, S. A., & Lafayette, C. (2023). 5′UTR Variant in KIT Associated With White Spotting in Horses. Journal of Equine Veterinary Science, 127, 104563.
Patterson Rosa, L., Martin, K., Vierra, M., Lundquist, E., Foster, G., Brooks, S. A., & Lafayette, C. (2022). A KIT Variant Associated with Increased White Spotting Epistatic to MC1R Genotype in Horses (Equus caballus). Animals, 12(15), 1958.
Patterson Rosa, L., Martin, K., Vierra, M., Foster, G., Brooks, S. A., & Lafayette, C. (2022). Non‐frameshift deletion on MITF is associated with a novel splashed white spotting pattern in horses (Equus caballus). Animal genetics, 53(4).
Patterson Rosa, L., Martin, K., Vierra, M., Foster, G., Lundquist, E., Brooks, S. A., & Lafayette, C. (2021). Two Variants of KIT Causing White Patterning in Stock-Type Horses. Journal of Heredity, 112(5), 447-451.
Martin, K., Rosa, L. P., Vierra, M., Foster, G., Brooks, S. A., & Lafayette, C. (2021). De novo mutation of KIT causes extensive coat white patterning in a family of Berber horses. Animal Genetics, 52(1), 135-137.
Bisbee, D., Carpenter, M. L., Hoefs-Martin, K., Brooks, S. A., & Lafayette, C. (2020). Identification of a novel missense variant in SLC45A2 associated with dilute snowdrop phenotype in Gypsy horses. Animal Genetics, 51(2), 342-343.
Holl, H. M., Pflug, K. M., Yates, K. M., Hoefs-Martin, K., Shepard, C., Cook, D. G., Lafayette, C., & Brooks, S. A. (2019). A candidate gene approach identifies variants in SLC45A2 that explain dilute phenotypes, pearl and sunshine, in compound heterozygote horses. Animal Genetics, 50(3), 271-274.
Henkel, J., Lafayette, C., Brooks, S. A., Martin, K., Patterson-Rosa, L., Cook, D., Jagannathan, V., & Leeb, T. (2019). Whole-genome sequencing reveals a large deletion in the MITF gene in horses with white spotted coat colour and increased risk of deafness. Animal Genetics, 50(2), 172-174.
Dürig, N., Jude, R., Holl, H., Brooks, S. A., Lafayette, C., Jagannathan, V., & Leeb, T. (2017). Whole genome sequencing reveals a novel deletion variant in the KIT gene in horses with white spotted coat colour phenotypes. Animal Genetics, 48(4), 483-485.
Holl, H. M., Brooks, S. A., Carpenter, M. L., Bustamante, C. D., & Lafayette, C. (2017). A novel splice mutation within equine KIT and the W15 allele in the homozygous state lead to all white coat color phenotypes. Animal Genetics, 48(4), 497–498.
Holl, H. M., Vanhnasy, J., Everts, R. E., Hoefs-Martin, K., Cook, D., Brooks, S. A., Carpenter, M. L., Bustamante, C. D., & Lafayette, C. (2017). Single nucleotide polymorphisms for DNA typing in the domestic horse. Animal Genetics, 48(6), 669-676.
Patterson Rosa, L., Campos, F. A., Martin, K., Vierra, M., Foster, G., Lundquist, E., Brooks, S. A., & Lafayette, C. (2022). Demystifying the Genetic Origins of the Mangalarga Horse Through the Influential Stallion Turbante J.O. Journal of equine veterinary science, 113, 103910.
Henkel J, Lafayette C, Brooks SA, Martin K, Patterson-Rosa L, Cook D, Jagannathan V, Leeb T. (2019). Whole-genome sequencing reveals a large deletion in the MITF gene in horses with white spotted coat colour and increased risk of deafness. Anim Genet. 50(2):172-174. doi: 10.1111/age.12762.
This publication shows an equine equivalent of Waardenburg Syndrome
Lordosis (L1, L2, L3, L4), also known as "Swayback", is a curvature or dip in the spine that is often seen in older horses. However, in the American Saddlebred, this condition also affects younger horses. These animals do not appear to experience pain from their condition and are still able to be used under saddle.
Malignant hyperthermia (MH) is a muscle disorder in which anesthesia, stress, or extreme exercise trigger a hyperthermic state. Symptoms include high temperature, increased heart rate, high blood pressure, sweating, acidosis, and muscle rigidity. If symptoms are not immediately resolved, death is likely to occur.
Myosin-Heavy Chain Myopathy (MY; previously "IMM") is a genetic muscle disease found most commonly in stock-type horses that can result in two different presentations, Immune-Mediated Myositis (IMM) and Nonexertional Rhabdomyolysis “tying up,” which are both characterized by muscle damage or loss. Both presentations are associated with the same genetic variant. Horses with MYHM may exhibit one or both presentations at different times in their lives, although some horses carrying the variant might not display any symptoms at all.
Myotonia (MYT) is a rare disorder involving a slowed relaxation of muscles after contraction. The most well-known example of myotonia is “fainting goats,” a breed that is characterized by sudden rigidy and/or falling over when startled. In the single documented horse, this resulted in a protruding third eyelid when excited, as well as problems with muscle stiffness.
